Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple inert gas elimination technique.

M P Hlastala

    Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    The multiple inert gas elimination technique is a powerful tool for analyzing lung ventilation-perfusion (VA/Q) distribution. Despite limitations, it remains essential for understanding pulmonary gas exchange.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Regional hypoxic pulmonary vasoconstriction in prone pigs.

    Journal of applied physiology (Bethesda, Md. : 1985)·2005
    Same author

    Highly soluble gases exchange in the pulmonary airways.

    Archives of physiology and biochemistry·2005
    Same author

    Characterization of bronchial-to-pulmonary communications.

    Archives of physiology and biochemistry·2005
    Same author

    Effects of vaporized perfluorocarbon on pulmonary blood flow and ventilation/perfusion distribution in a model of acute respiratory distress syndrome.

    Anesthesiology·2001
    Same author

    Determination of regional ventilation and perfusion in the lung using xenon and computed tomography.

    Journal of applied physiology (Bethesda, Md. : 1985)·2001
    Same author

    Perfluorocarbon enhanced gas exchange: the easy way.

    American journal of respiratory and critical care medicine·2001
    Same journal

    Metabolic control of cardiac output response to exercise in McArdle's disease.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    Hypoxic insomnia: effects of carbon monoxide and acclimatization.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    Quiet-breathing vs. panting methods for determination of specific airway conductance.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    A new method for raising neonatal rabbits in a hypoxic environment.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    Modification of the cutaneous vascular response to exercise by local skin temperature.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    Temperature regulation during treadmill exercise in the rat.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    See all related articles

    Area of Science:

    • Physiology
    • Respiratory Medicine
    • Pulmonary Function Testing

    Background:

    • Pulmonary gas exchange understanding has evolved significantly since the early 1900s.
    • The ventilation-perfusion (VA/Q) distribution is a key aspect of lung function.

    Purpose of the Study:

    • To highlight the significance of the multiple inert gas elimination technique (MIGET) in assessing VA/Q distribution.
    • To discuss the capabilities and limitations of MIGET in analyzing pulmonary gas exchange.

    Main Methods:

    • Infusion of six inert gases.
    • Measurement of mixed venous, arterial, and mixed expired gas concentrations.
    • Mathematical modeling to determine VA/Q distribution, shunt, and dead space.

    Main Results:

    Related Experiment Videos

    • MIGET allows for the differentiation of shunt, dead space, and the overall VA/Q pattern.
    • The technique provides a comprehensive analysis of pulmonary gas exchange.

    Conclusions:

    • The multiple inert gas elimination technique is the most potent method available for analyzing pulmonary gas exchange.
    • Awareness of the technique's limitations is crucial to prevent misinterpretation of results.