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[Human peripheral neurolymphomatosis].

J O Trelles, L Trelles

    Revue Neurologique
    |January 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Human neurolymphomatosis presents as ascending paralysis with nerve infiltration. This condition may be a viral polyradiculoneuritis linked to Marek's disease virus, particularly in poultry farm workers.

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    Area of Science:

    • Neurology
    • Oncology
    • Virology

    Background:

    • Human neurolymphomatosis is a rare neurological disorder.
    • Understanding its clinical and pathological features is crucial for diagnosis and treatment.

    Observation:

    • Two new cases of human neurolymphomatosis were analyzed.
    • Clinical symptoms include flaccid ascending paralysis, absent reflexes, muscle pain, and sphincter disturbances.
    • Pathology reveals lymphoid cell infiltration of the peripheral nervous system, sometimes extending to the central nervous system.

    Findings:

    • The study reviewed 9 cases, including the 2 new ones.
    • Clinical and histopathologic findings suggest a possible link to Marek's disease virus.
    • Affected nerves show increased size due to lymphoid infiltration.

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    Implications:

    • This research suggests neurolymphomatosis might be a viral polyradiculoneuritis.
    • The findings support investigating Marek's disease virus as a potential cause.
    • Further research could clarify the etiology and improve patient outcomes.