Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunopathogenic mechanisms in tissue damage.

G Bendixen

    Acta Endocrinologica. Supplementum
    |January 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Understanding immunopathogenic damage requires analyzing specific immune responses and complex non-specific mediating systems. Critical evaluation of these factors is key to advancing knowledge of diseases like diabetes mellitus.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Quantitative assessment of clinical disease status in primary Sjögren's syndrome. A cross-sectional study using a new classification model.

    Scandinavian journal of rheumatology·1997
    Same author

    A new model for classification of disease manifestations in primary Sjögren's syndrome: evaluation in a retrospective long-term study.

    Journal of internal medicine·1996
    Same author

    [Molecular biology and rheumatology].

    Ugeskrift for laeger·1995
    Same author

    Increased expression of complement receptor type 1 (CR1, CD35) on human peripheral blood T lymphocytes after polyclonal activation in vitro.

    Immunologic research·1995
    Same author

    [Systemic lupus erythematosus. 1. Disease manifestations, infections, thrombotic episodes, causes of death and survival in a case load of 173 patients followed for 13.9 years].

    Ugeskrift for laeger·1991
    Same author

    [Systemic lupus erythematosus. 2. Factors of predictive significance for survival].

    Ugeskrift for laeger·1991
    Same journal

    Studies on parathyroidal function in relation to hormonal influences and dietetic conditions.

    Acta endocrinologica. Supplementum·2014
    Same journal

    Advance abstracts of papers. Scandinavian Society for the Study of Diabetes: 23rd annual meeting. May 5-7, 1988, Bergen.

    Acta endocrinologica. Supplementum·1988
    Same journal

    Program of plenary sessions and advance abstracts of short communications. 32. Symposium Deutsche Gesellschaft für Endokrinologie. Hamburg, February 17-20, 1988.

    Acta endocrinologica. Supplementum·1988
    Same journal

    The use of GnRH analogues in combination with exogenous gonadotropins in infertile women.

    Acta endocrinologica. Supplementum·1988
    Same journal

    Precocious and delayed sexual development in children.

    Acta endocrinologica. Supplementum·1988
    Same journal

    Pulsatile GnRH therapy for the induction of ovulation in hypogonadotropic hypogonadism.

    Acta endocrinologica. Supplementum·1988
    See all related articles

    Area of Science:

    • Immunology
    • Pathology
    • Cell Biology

    Background:

    • Immunopathogenic damage knowledge stems from in vitro, in vivo, and clinical studies across species.
    • Analyzing immunological processes causing tissue damage necessitates evaluating specific and non-specific factors.

    Purpose of the Study:

    • To critically assess the mechanisms of immunologically specific initiating factors and non-specific mediating factors in tissue damage.
    • To improve the understanding of immunopathogenesis in clinical disorders, including diabetes mellitus.

    Main Methods:

    • Evaluation of specific immune components: antigen identity/location, antibody identity/location, and reactive lymphocytes.
    • Analysis of non-specific mediating systems: complement, coagulation, granulocyte/macrophage functions, chemotaxis, mast cells, and phagocytosis.

    Related Experiment Videos

  • Integration of data from diverse sources including in vitro, in vivo, and clinical observations.

    • Main Results:

    • Hypothesizing immunopathogenic damage mechanisms requires detailed information on specific immune components.
    • Non-specific mediating systems, triggered by specific immune reactions, are the primary inducers of tissue damage.
    • The complexity of non-specific mediation necessitates investigating system interactions.

    Conclusions:

    • Current understanding of human immunopathogenesis relies heavily on analogies and assumptions.
    • Asking pertinent questions and critically evaluating answers are crucial for progress.
    • Improved understanding of immunopathogenesis in diabetes mellitus and other disorders is achievable through rigorous scientific inquiry.