Treatment of superficial and deep-seated mycoses with oral ketoconazole

Oral ketoconazole was given to 50 patients, 36 with superficial and 14 with deep-seated mycoses. Satisfactory results were obtained in dermatophytoses, pityriasis versicolor, and chronic mucocutaneous candidiasis. Paracoccidioidomycosis also responded well to ketoconazole therapy. The authors' experience in patients with histoplasmosis and aspergillosis does not make it possible to express a firm view on the efficacy of the drug. Ketoconazole is not the recommended drug for treatment of sporotrichosis.