[Monilial granuloma treated successfully with ketoconazole over a period of 30 months]

A case of monilial granuloma of 12 years duration is being successfully treated with ketoconazole administered orally in doses of 200 mg per day. Trush, onyxis and keratotic granulomatous lesions of the face and hands have dramatically regressed. In view of persistent anomalies of cellular immunity and complete deficiency in serum and salivary IgA, treatment with ketoconazole at the same dosage level has now been continuously pursued for 30 months without any evidence of toxicity.