Related Experiment Videos
Typhlitis: a cause of gastrointestinal hemorrhage in children
AJR. American Journal of Roentgenology
|October 1, 1984
Insights
Typhilitis in children with acute leukemia can cause severe intestinal bleeding. Arteriography revealed specific cecal and mesenteric vascular changes, successfully treated with various therapies.
Area of Science:
- Pediatric Oncology
- Gastrointestinal Radiology
- Vascular Surgery
Background:
- Typhilitis, an inflammation of the cecum, is a serious complication in children undergoing chemotherapy for acute leukemia.
- Severe intestinal hemorrhage can occur in these patients, posing a significant management challenge.
Observation:
- This study describes three pediatric cases of typhilitis associated with acute leukemia and severe gastrointestinal bleeding.
- Arteriographic examination revealed characteristic findings including cecal hypervascularity, mucosal staining, superficial ulcer opacification, and arteriovenous shunting into mesenteric veins.
Findings:
- The arteriographic findings provide crucial insights into the vascular pathology of typhilitis in this context.
- Successful management was achieved through diverse therapeutic approaches: medical, surgical, and interventional embolization.
Implications:
- Understanding these arteriographic findings aids in diagnosing and managing typhilitis-related hemorrhage in pediatric leukemia.
- The successful application of varied treatments highlights the importance of a multidisciplinary approach for optimal patient outcomes.
Abstract:
Three children with typhilitis complicating acute leukemia and presenting with severe intestinal hemorrhage are described. The arteriographic findings were hypervascularity of the cecum with intense mucosal staining, opacification of superficial ulcers, and arteriovenous shunting into dilated mesenteric veins. The three children were managed successfully with medical, surgical, and embolic therapies, respectively.