Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic ventilatory failure caused by abnormal respiratory pattern generation during sleep.

T D Bradley, A Day, R H Hyland

    The American Review of Respiratory Disease
    |October 1, 1984
    PubMed
    Summary

    A patient experienced chronic respiratory failure due to abnormal breathing patterns during sleep. Diaphragmatic pacing corrected this, resolving the failure and highlighting the importance of sleep breathing patterns.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Health engagement sessions as a means of addressing reproductive health inequalities in a population of Afghan women during Operation ALLIED SOLACE.

    BMJ military health·2022
    Same author

    Habitual dietary fibre and prebiotic intake is inadequate in patients with inflammatory bowel disease: findings from a multicentre cross-sectional study.

    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association·2020
    Same author

    Albumin and calcium reference interval using healthy individuals and a data-mining approach.

    Annals of clinical biochemistry·2020
    Same author

    In search of a one plan solution for VMAT post-mastectomy chest wall irradiation.

    Journal of applied clinical medical physics·2020
    Same author

    The effect of different analytical platforms and methods on the performance of population-specific adjusted calcium equation.

    Annals of clinical biochemistry·2020
    Same author

    The stability of imaging biomarkers in radiomics: a framework for evaluation.

    Physics in medicine and biology·2019

    Area of Science:

    • Pulmonology
    • Sleep Medicine
    • Neurology

    Background:

    • Investigated a 67-year-old man with a 4-year history of chronic ventilatory failure.
    • Ruled out restrictive/obstructive defects and performed unremarkable neurologic investigations.
    • Confirmed normal minute ventilation response to inhaled CO2 during wakefulness.

    Observation:

    • During sleep, the patient exhibited a rapid, shallow breathing pattern.
    • Minute ventilation during sleep (6.7 L/min) was comparable to wakefulness (7.2 L/min).
    • No evidence of upper airway obstruction was detected during sleep.

    Findings:

    • Sleep-associated abnormal breathing pattern led to increased dead space ventilation.
    • Inadequate alveolar ventilation resulted in hypoxemia and hypercapnia during sleep.

    Related Experiment Videos

  • Diaphragmatic pacing corrected the abnormal ventilatory pattern and resolved chronic respiratory failure.

    • Implications:

    • Disordered respiratory pattern during sleep can cause chronic ventilatory failure.
    • This can occur even with normal respiratory drive and absence of lung disease.
    • Highlights the critical role of sleep-specific respiratory control mechanisms.