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One-hour and half, high-surface-area haemodiafiltration: a feasibility study
C Basile1, A Di Maggio, S Longo
1Department of Nephrology, General Hospital, Taranto, Italy.
In order to explore the limitations of further shortening of dialysis time, six uraemic patients underwent three different dialysis treatments: haemodiafiltration (HDF) of 180 min with a polyacrylonitrile membrane (1 m2); standard haemodialysis (SH) of 270 min with a cuprophan membrane (1 m2); 90 min, 2 m2 haemodiafiltration (H HDF) with two RP6 in series, dialysate coursed through the two dialysers in parallel and postdilution reinjection of 220 mEq/L of Na+ and 100 mEq/L of bicarbonate after each dialyser. Clearances were extremely more elevated in H HDF than in SH; urea extraction index was significantly higher in SH, but inulin extraction index was significantly lesser in SH than in H HDF.
In order to explore the limitations of further shortening of dialysis time, six uraemic patients underwent three different dialysis treatments: haemodiafiltration (HDF) of 180 min with a polyacrylonitrile membrane (1 m2); standard haemodialysis (SH) of 270 min with a cuprophan membrane (1 m2); 90 min, 2 m2 haemodiafiltration (H HDF) with two RP6 in series, dialysate coursed through the two dialysers in parallel and postdilution reinjection of 220 mEq/L of Na+ and 100 mEq/L of bicarbonate after each dialyser. Clearances were extremely more elevated in H HDF than in SH; urea extraction index was significantly higher in SH, but inulin extraction index was significantly lesser in SH than in H HDF.