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Related Experiment Videos

Pseudophakic bullous keratopathy.

D M Taylor, B F Atlas, K G Romanchuk

    Ophthalmology
    |January 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Pseudophakic bullous keratopathy (PBK) is a growing cause for corneal transplants, especially with iris-supported lenses. Newer surgical techniques significantly reduce PBK incidence, offering promising visual outcomes.

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    Area of Science:

    • Ophthalmology
    • Corneal Surgery
    • Cataract Surgery

    Background:

    • Pseudophakic bullous keratopathy (PBK) is an emerging complication following cataract surgery.
    • It is increasingly becoming the primary indication for penetrating keratoplasty.
    • The incidence of PBK with iris-supported intraocular lenses (IOLs) is notably higher than aphakic bullous keratopathy (ABK).

    Purpose of the Study:

    • To evaluate the incidence of PBK following intracapsular cataract extraction (ICCE) with iris-supported IOLs.
    • To analyze etiologic factors, prevention strategies, and outcomes of penetrating keratoplasty for PBK.
    • To assess the impact of planned extracapsular cataract extraction (ECCE) with posterior chamber lens (PCL) insertion on PBK rates.

    Main Methods:

    • Retrospective review of 800 ICCEs with iris-supported IOLs (1975-1979) to determine PBK incidence.

    Related Experiment Videos

  • Review of 3,000 simple ICCEs (1955-1980) for ABK incidence.
  • Analysis of 81 corneal transplants performed for PBK (1977-1981).
  • Comparison of PBK rates before and after implementing ECCE with PCL insertion (1979-1982).

    • Main Results:

    • PBK developed in 4.3% of patients (34/800) after ICCE with iris-supported IOLs, averaging two years post-surgery.
    • ABK occurred in 0.8% of patients (24/3,000) after simple ICCEs.
    • Penetrating keratoplasty for PBK yielded an 88% graft clarity rate, but visual results were often compromised by posterior segment disease.
    • Planned ECCE with PCL insertion reduced the PBK incidence to 0.3% (1/300).

    Conclusions:

    • PBK following ICCE with iris-supported IOLs is a serious, often multifactorial condition.
    • While penetrating keratoplasty can restore corneal clarity, associated posterior segment issues impact final visual acuity.
    • Transitioning to planned ECCE with PCLs has significantly decreased PBK incidence, showing promising, albeit preliminary, results.