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Related Experiment Videos

Facultative gram-negative enteric rods in persistent periapical infections.

M Haapasalo, H Ranta, K T Ranta

    Acta Odontologica Scandinavica
    |January 1, 1983
    PubMed
    Summary

    Persistent periapical infections resistant to standard treatments were investigated. Targeted antibiotic therapy based on bacterial susceptibility testing proved successful for these challenging cases.

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    Area of Science:

    • Microbiology
    • Endodontics
    • Infectious Diseases

    Background:

    • Persistent periapical infections pose a clinical challenge, often resisting conventional root canal therapy.
    • Previous treatments involving penicillin or erythromycin were ineffective in these two cases.

    Observation:

    • Bacteriological samples were aseptically collected from root canals of two patients with persistent periapical infections.
    • Cultivation on specialized media identified Enterobacter cloacae in one case and Klebsiella pneumoniae and enterococci in the second case.
    • Obligately anaerobic bacteria were not detected in either case.

    Findings:

    • The identified facultative anaerobic enteric rods were susceptible to specific antibiotics.
    • Tailored antibiotic therapy, guided by in vitro susceptibility testing, led to successful treatment outcomes.
    • This highlights the importance of identifying causative agents for effective periapical infection management.

    Implications:

    • Facultative enteric rods can be implicated in persistent periapical infections unresponsive to empirical antibiotic treatment.
    • Susceptibility testing is crucial for guiding effective antimicrobial strategies in endodontic infections.
    • Understanding the microbial etiology, including facultative anaerobes, is vital for successful endodontic treatment.

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