Thrombosis following phlebography with high-osmolar and low-osmolar contrast media

In a prospective, randomised double blind study of 47 phlebographies, diatrizoate and ioxaglate were compared with regard to possible postphlebographic thrombosis proved by 125I-Fibrinogen uptake test. A significantly lower rate of postphlebographic thrombosis was registered when the low-osmolar ioxaglate was used.