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Primary immune responses to H-Y in BALB/c-H-2k mice

R B Ashman

    Immunogenetics
    |January 1, 1983
    PubMed

    Female mice of the H-2k haplotype have been thought not to reject primary grafts of male skin. However, most BALB/c-H-2k female mice bred in our colony rejected syngeneic male grafts. Graft rejection was sufficient to prime the mice for the subsequent generation of H-Y-specific cytotoxic T cells and delayed-type hypersensitivity responses.

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