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Updated: Oct 14, 2026

Detection and Enrichment of Rare Antigen-specific B Cells for Analysis of Phenotype and Function
Published on: February 16, 2017
The reactivity of Reed-Sternberg cells with monoclonal antisera at thin section and ultrastructural levels
Abstract:
In an attempt to improve the morphology of Reed-Sternberg cells after immunochemical procedures, the biotin-avidin technique has been used. Satisfactory morphology was obtained at the level of both light and electron microscopy. Reed-Sternberg cells failed to react with a monoclonal antimonocyte serum but gave positive results with anti-1a and FMC7, a monoclonal anti-B cell serum. Positive results were also obtained with FMC1 and B1 both of which are monoclonal B cell antisera.
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