[Effect of beta-1,3 glucan and other immunomodulators of microbial origin on experimental leprosy in mice]

The effect of beta-1,3 glucan and cell walls of S. cerevisiae on one hand and of peptidoglycans from strain LDC 15 and C. renale and cell walls of C. Hofmannii on the other hand has been investigated in the experimental leprosy infection in mice. beta-1,3 glucan, by enhancing the function of the reticulo-endothelial system, is the most active inhibitor of the multiplication of Hansen's bacilli. Peptidoglycan of strain LDC 15 is less active and seems non specific.