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Related Experiment Videos

[Microbiological studies before and after endoscopic papillotomy (EPT)].

R Ansorg, U R Fölsch, N Kieslich

    Infection
    |September 1, 1983
    PubMed
    Summary

    Endoscopes used in endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic papillotomy (EPT) procedures can become contaminated, potentially leading to infections. Enhanced disinfection and antibiotic prophylaxis are recommended to reduce risks for patients.

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    [DNA demonstration of Chlamydia trachomatis and Neisseria gonorrhoeae in urine specimens of medical students].

    Deutsche medizinische Wochenschrift (1946)·1999

    Area of Science:

    • Gastroenterology
    • Infectious Diseases
    • Medical Microbiology

    Background:

    • Choledocholithiasis patients undergoing endoscopic procedures are at risk of infection.
    • Endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic papillotomy (EPT) involve invasive manipulation of the duodeno-biliary tract.

    Purpose of the Study:

    • To assess the microbiological contamination of endoscopes during ERCP and EPT.
    • To investigate the incidence of bacteriaemia and changes in duodenal/biliary flora post-procedure.
    • To determine the antibiotic sensitivity of isolated bacteria.

    Main Methods:

    • Microbiological examination of 17 choledocholithiasis patients undergoing ERCP and EPT.
    • Analysis of endoscope contamination rates.
    • Monitoring for bacteriaemia and duodenal/biliary flora changes over four months.

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  • Antibiotic susceptibility testing of isolated bacteria.

    • Main Results:

    • Endoscope contamination occurred in 56% of 34 procedures.
    • Oral flora transfer to the duodeno-biliary region was observed in 9% of interventions.
    • Bacteriaemia occurred in 17% of patients post-EPT.
    • Increased bacterial counts and dominance of Klebsiella-Enterobacter-Serratia group noted in duodenal/biliary juice after four months.
    • Over 80% of isolates were sensitive to cefotaxime, cefamandole, and co-trimoxazole.

    Conclusions:

    • Endoscopic procedures carry a significant risk of microbiological contamination and subsequent infection.
    • Strict adherence to endoscope disinfection protocols is crucial.
    • Periendoscopic antibiotic prophylaxis should be considered to minimize infection risks.