Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Current concepts. Serum osmolality. Uses and limitations.

F J Gennari

    The New England Journal of Medicine
    |January 12, 1984
    PubMed
    Summary

    Serum osmolality testing offers insights into serum water content and detects foreign solutes. Calculating effective osmolality using sodium and glucose levels is a direct method for assessing tonicity and guiding therapy.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Recent advances in the management of hypertension in the elderly.

    Current hypertension reports·2000
    Same author

    Acid-base balance in dialysis patients.

    Seminars in dialysis·2000
    Same author

    Hypertension in the elderly: management issues.

    Coronary artery disease·1999
    Same author

    Hypokalemia.

    The New England journal of medicine·1998
    Same author

    Effect of acute increases in filtered HCO3- on renal hydrogen transporters: II. H(+)-ATPase.

    Kidney international·1997
    Same author

    Nephrology core curriculum. The American Society of Nephrology and the American Society of Nephrology Training Program Directors Committee.

    Journal of the American Society of Nephrology : JASN·1997

    Area of Science:

    • Clinical Medicine
    • Biochemistry
    • Nephrology

    Background:

    • Serum osmolality is a key clinical measurement.
    • Deviations in serum water content and presence of foreign solutes can be detected.
    • Direct assessment of tonicity homeostasis requires specific calculations.

    Purpose of the Study:

    • To clarify the clinical utility of serum osmolality measurement.
    • To establish a method for assessing tonicity homeostasis.
    • To guide therapeutic decisions based on osmolality calculations.

    Main Methods:

    • Comparison of measured serum osmolality with calculated osmolality from major serum solutes.
    • Calculation of effective osmolality using serum sodium and glucose concentrations.

    Main Results:

    • Measured osmolality compared to calculated osmolality reveals deviations in serum water and presence of foreign solutes.
    • Effective osmolality calculation from sodium and glucose is a direct indicator of tonicity.
    • This calculation provides essential information for therapeutic decisions.

    Conclusions:

    • Serum osmolality measurement has specific clinical applications.
    • Effective osmolality calculation is a reliable method for assessing tonicity.
    • This approach aids in clinical decision-making for managing fluid and electrolyte balance.

    Related Experiment Videos