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Updated: Aug 10, 2026

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
[Kidney-related hypertension]
Abstract:
Secondary hypertension is due to renal parenchymal disease in 3 of 4 pediatric patients. Among the unilateral renal diseases, reflux nephropathy is the most important condition, leading to hypertension in 10-20% of such patients (hence the need for yearly blood pressure recordings). Among the bilateral renal diseases, acute glomerulonephritis is still the best known cause of hypertension, although the various forms of chronic glomerulonephritis and renal insufficiency are nowadays of greater importance. Newer forms of hypertension may be observed after catheterisation of the umbilical artery in newborns, and after renal transplantation. Effective therapy of hypertension is essential.
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