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The decline of stroke.

J P Whisnant

    Stroke
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Stroke incidence and mortality have significantly decreased, primarily due to effective hypertension treatment. This decline, particularly in cerebral infarction and hemorrhage, was observed earlier in women than men.

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    Area of Science:

    • Neurology
    • Public Health
    • Epidemiology

    Background:

    • Stroke mortality in the US has declined since 1900.
    • Rochester, Minnesota, experienced a 76% decline in stroke mortality since 1950.
    • Declines are attributed to reduced incidence of cerebral infarction and cerebral hemorrhage.

    Purpose of the Study:

    • To investigate the causes behind the observed decline in stroke mortality.
    • To analyze trends in stroke incidence and their correlation with risk factors.
    • To evaluate the impact of hypertension treatment on stroke rates.

    Main Methods:

    • Analysis of historical stroke mortality and incidence data.
    • Comparison of trends between genders.
    • Correlation analysis with hypertension prevalence and treatment effectiveness.

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    Main Results:

    • A significant decrease in stroke incidence, particularly cerebral infarction and hemorrhage, was the primary driver of mortality decline.
    • The reduction in stroke incidence was observed in women 10-15 years earlier than in men.
    • Hypertension surveys indicated increasing effectiveness of antihypertensive medications, with earlier impact noted in women.

    Conclusions:

    • The available evidence strongly suggests that the effective treatment of hypertension is the principal factor contributing to the decline in stroke mortality.
    • The earlier decline in stroke incidence among women aligns with earlier observed effectiveness of antihypertensive treatments in this demographic.
    • Public health initiatives targeting hypertension management are crucial for continued reduction of stroke burden.