Tolerability and efficacy of a slow-release indomethacin tablet in ankylosing spondylitis

The efficacy and tolerability of a new formulation of slow-release indomethacin tablet was compared in a double-blind cross-over manner with a conventional indomethacin capsule in 30 patients with ankylosing spondylitis. Gastrointestinal side-effects and dizziness were less frequent during the slow-release tablet period than during the capsule period.