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[Salmonella meningitis].

M Ceyhan, M Ertuğrul, S Göğüş

    Mikrobiyoloji Bulteni
    |July 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    A four-month-old boy developed Salmonella Typhimurium meningitis after initial treatment for pneumonia. Despite antibiotic therapy, the infant succumbed to the infection, highlighting the severity of Salmonella meningitis in neonates.

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    Area of Science:

    • Pediatrics
    • Infectious Diseases
    • Neonatal Care

    Background:

    • Salmonella Typhimurium is a significant cause of bacterial meningitis in infants.
    • Early diagnosis and appropriate antibiotic treatment are crucial for managing neonatal meningitis.

    Observation:

    • A four-month-old boy presented with symptoms of meningitis, including fever, vomiting, stiff neck, and bulging fontanel.
    • Cerebrospinal fluid (CSF) and blood cultures confirmed Salmonella Typhimurium infection.
    • The infant had a history of staphylococcal pneumonia, pyo-pneumothorax, cardiac failure, and anemia.

    Findings:

    • The isolated Salmonella Typhimurium strain was sensitive only to trimethoprim-sulfamethoxazole and netilmicin.
    • Despite treatment with these antibiotics, the patient's condition deteriorated, leading to expiration.

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  • Postmortem examination confirmed Salmonella Typhimurium in meningeal tissue and CSF.

    • Implications:

    • This case underscores the critical need for prompt recognition and aggressive management of Salmonella meningitis in infants.
    • The limited antibiotic sensitivity observed highlights potential challenges in treating invasive Salmonella infections.
    • Further research into effective therapeutic strategies for neonatal Salmonella meningitis is warranted.