Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The use of radiolabeled anti-CD33 antibody to augment marrow irradiation prior to marrow transplantation for acute myelogenous leukemia.

Transplantation·1992
Same author

Methylation of the DXS255 hypervariable locus 5' CCGG site may be affected by factors other than X-chromosome activation status.

Genomics·1992
Same author

Bone marrow transplantation: past experiences and future prospects.

Seminars in oncology·1992
Same author

Donor alloreactivity may predict acute graft-versus-host disease in HLA-matched bone marrow transplantation for leukemia in early remission.

European journal of haematology·1992
Same author

Mixed leukocyte culture reactivity and graft-versus-host disease in HLA-identical marrow transplantation for leukemia.

Bone marrow transplantation·1992
Same author

Acceptance of the George M. Kober Medal.

Transactions of the Association of American Physicians·1992
Same journal

Dupilumab Emerges as an Effective Antibody Therapy for Eosinophilic Esophagitis.

Annual review of medicine·2026
Same journal

CAR T Cell Toxicities and Emerging Treatment Strategies.

Annual review of medicine·2026
Same journal

Transthyretin Amyloid Cardiomyopathy: A Rapidly Evolving Landscape.

Annual review of medicine·2026
Same journal

Accessibility of Somatic Genetic Testing for Cancer Treatment Decisions.

Annual review of medicine·2026
Same journal

Diffuse Parenchymal Lung Disease: Updates in Pathophysiology and Management.

Annual review of medicine·2026
Same journal

Revascularization for Ischemic Cardiomyopathy: Disproving the 45-Year-Old Concept of Hibernating Myocardium.

Annual review of medicine·2026
See all related articles

Related Experiment Video

Updated: May 10, 2026

Transduction-Transplantation Mouse Model of Myeloproliferative Neoplasm
08:12

Transduction-Transplantation Mouse Model of Myeloproliferative Neoplasm

Published on: December 22, 2016

Indications for marrow transplantation.

E D Thomas, R A Clift, R Storb

    Annual Review of Medicine
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Marrow grafting, now a primary treatment for many diseases, has evolved beyond end-stage care. This summary covers donor/recipient selection and outcomes for marrow transplantation across diverse conditions.

    More Related Videos

    Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis
    08:00

    Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis

    Published on: May 26, 2021

    Simplified Intrafemoral Injections Using Live Mice Allow for Continuous Bone Marrow Analysis
    06:28

    Simplified Intrafemoral Injections Using Live Mice Allow for Continuous Bone Marrow Analysis

    Published on: November 10, 2023

    Related Experiment Videos

    Last Updated: May 10, 2026

    Transduction-Transplantation Mouse Model of Myeloproliferative Neoplasm
    08:12

    Transduction-Transplantation Mouse Model of Myeloproliferative Neoplasm

    Published on: December 22, 2016

    Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis
    08:00

    Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis

    Published on: May 26, 2021

    Simplified Intrafemoral Injections Using Live Mice Allow for Continuous Bone Marrow Analysis
    06:28

    Simplified Intrafemoral Injections Using Live Mice Allow for Continuous Bone Marrow Analysis

    Published on: November 10, 2023

    Area of Science:

    • Hematology
    • Oncology
    • Immunology

    Background:

    • Marrow grafting was initially a last resort for end-stage patients.
    • Its application has significantly expanded in modern medicine.

    Purpose of the Study:

    • To summarize the current role of marrow grafting in treating diseases.
    • To review donor and recipient selection criteria.
    • To present outcomes of marrow transplantation for various conditions.

    Main Methods:

    • Literature review of marrow transplantation studies.
    • Analysis of donor and recipient selection protocols.
    • Synthesis of results from diverse disease applications.

    Main Results:

    • Marrow transplantation is now a preferred treatment for numerous malignant and nonmalignant conditions.
    • Successful donor and recipient matching is crucial for positive outcomes.
    • Transplantation efficacy varies by disease and stage.

    Conclusions:

    • Marrow grafting has transitioned from salvage therapy to a frontline treatment.
    • Careful patient and donor selection optimizes marrow transplantation success.
    • Further research continues to refine marrow transplantation protocols.