Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Breathing pattern during induced bronchoconstriction.

T S Chadha, A W Schneider, S Birch

    Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
    |April 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Planning the future of oral health care workforce: Moving beyond demographic change.

    Community dental health·2023
    Same author

    Modelling a Consultant Workforce for the United Kingdom: needs-based planning for Dental Public Health.

    Community dental health·2023
    Same author

    Abstracts of presentations to the Annual Meetings of the Canadian Society of Colon and Rectal Surgeons Canadian Association of General Surgeons Canadian Association of Thoracic Surgeons: Canadian Surgery Forum, Toronto, Ont., September 6-9, 2007.

    Canadian journal of surgery. Journal canadien de chirurgie·2023
    Same author

    Perioperative management of a parturient with VACTERL association for a caesarean section.

    Anaesthesia reports·2023
    Same author

    Who are the 10%? Characteristics of the populations and communities receiving fluoridated water in England.

    Community dental health·2022
    Same author

    Scintillation light detection in the 6-m drift-length ProtoDUNE Dual Phase liquid argon TPC.

    The European physical journal. C, Particles and fields·2022
    Same journal

    Metabolic control of cardiac output response to exercise in McArdle's disease.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    Hypoxic insomnia: effects of carbon monoxide and acclimatization.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    Quiet-breathing vs. panting methods for determination of specific airway conductance.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    A new method for raising neonatal rabbits in a hypoxic environment.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    Modification of the cutaneous vascular response to exercise by local skin temperature.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    Temperature regulation during treadmill exercise in the rat.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    See all related articles

    Mild bronchoconstriction alters breathing by increasing mean inspiratory flow and lung volume. Inspiratory ventilation increases initially but plateaus with severe constriction, showing the body

    Area of Science:

    • Respiratory Physiology
    • Pulmonary Function Testing

    Background:

    • Bronchoconstriction, a narrowing of airways, can affect breathing patterns.
    • Understanding these changes is crucial for diagnosing and managing respiratory conditions.

    Purpose of the Study:

    • To investigate how mild increases in respiratory resistance impact breathing patterns in normal subjects.
    • To differentiate the effects of bronchoconstriction from normal breathing mechanics.

    Main Methods:

    • Subjects breathed naturally and through a mouthpiece connected to a pneumotachograph.
    • Respiratory inductive plethysmography monitored breathing patterns.
    • Methacholine aerosol was used to induce dose-dependent bronchoconstriction, with specific airway conductance (sGaw) reductions of 25% (PD25), 35% (PD35), and 55% (PD55).

    Related Experiment Videos

    Main Results:

    • Methacholine increased mean inspiratory flow (VT/TI) and end-expiratory lung volume.
    • Inspiratory ventilation (VI) increased with mild-to-moderate bronchoconstriction (PD25, PD35) but plateaued at severe levels (PD55).
    • Breathing pattern remained unchanged when subjects breathed through a mouthpiece, suggesting mouth breathing alters the response.

    Conclusions:

    • Mild-to-moderate bronchoconstriction is characterized by increased respiratory drive (mean inspiratory flow) and pulmonary hyperinflation.
    • The body's ventilatory response plateaus at higher levels of airway resistance.
    • Mouth breathing may mask the breathing pattern alterations induced by bronchoconstriction.