Related Experiment Video
Updated: Aug 7, 2026
11:37
Measurement of Cellular Chemotaxis with ECIS/Taxis
Published on: April 1, 2012
Advantages and limitations of methods for measuring cellular chemotaxis and chemokinesis
Molecular and Cellular Biochemistry
|April 1, 1984
Abstract:
Cell migration is an important component of many physiological reactions, for example inflammation, wound healing and formation of atherosclerotic lesions. This review summarizes the methods currently available for examining cell movement in vitro. The applications of each method, and its particular advantages and disadvantages are discussed. Techniques are described for preparing purified leukocyte populations for use in migration studies and for differentiating between chemotactic and chemokinetic cell migration.
Related Concept Videos
01:09Cell Migration
Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.
01:21Chemotaxis and Direction of Cell Migration
Cells can detect chemical cues in their environment and reorganize the cytoskeleton to migrate toward them or away from them. This directional migration, called chemotaxis, is essential during embryogenesis and development, immune response, tissue repair and regeneration, and reproduction. These chemical cues can either attract or repel the cell's movement. For example, axon development is determined by a combination of chemoattractants and chemorepellents that direct the growing axon towards...
01:27Chemotaxis in E. coli
Chemotaxis in Escherichia coli is a sensory-driven motility mechanism that enables bacteria to navigate chemical gradients, moving toward beneficial environments while avoiding harmful conditions. This process relies on a signal transduction system integrating external chemical cues with flagellar motor control.Chemoreceptors and Signal DetectionE. coli detects chemical gradients through methyl-accepting chemotaxis proteins (MCPs), which are membrane-bound chemoreceptors that sense attractants...