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[Clinical aspects of urinary tract infection by Serratia marcescens]
Abstract:
A study was made of the actual status of urinary tract infection induced by Serratia marcescens on a total of 88 patients who were admitted to our University Hospital in 1981 approximately 1982, and in whose urines not less than 10(4)/ml of S. marcescens were found. An investigation into the background factors of these patients revealed that indwelling catheter, operation for malignancy and use of antibiotics were the major factors responsible for the infection. S. marcescens was found to coexist with P. aeruginosa in not a few cases. The pathogens were highly susceptible to ST compound preparations, DKB and GM, and the pathogens in only 7 of the patients were tolerant to all of these antibiotics. None of the patients died of S. marcescens infection.
Insights
Serratia marcescens urinary tract infections were studied in 88 patients. Major risk factors included catheter use and prior operations, with most strains susceptible to common antibiotics.
Area of Science:
- Urology
- Infectious Diseases
- Microbiology
Context:
- Urinary tract infections (UTIs) caused by Serratia marcescens are a concern in hospital settings.
- This study examines UTIs in patients admitted to a University Hospital between 1981 and 1982.
Purpose:
- To investigate the prevalence and characteristics of Serratia marcescens-induced UTIs.
- To identify key risk factors associated with these infections.
- To assess the antibiotic susceptibility patterns of Serratia marcescens.
Summary:
- Eighty-eight patients with significant S. marcescens bacteriuria (≥10(4)/ml) were analyzed.
- Indwelling catheterization, surgery for malignancy, and antibiotic use were identified as primary risk factors.
- Serratia marcescens frequently co-occurred with Pseudomonas aeruginosa.
- High susceptibility was observed for ST compound preparations, DKB, and GM; only 7 patients showed resistance to all tested antibiotics.
- No fatalities were attributed to S. marcescens infection.
Impact:
- Provides insights into the epidemiology of Serratia marcescens UTIs in a hospital cohort.
- Highlights critical risk factors for targeted prevention strategies.
- Informs clinical management by detailing antibiotic susceptibility, guiding effective treatment choices.