Related Experiment Video
Updated: Aug 12, 2026

Human Dupuytren's Ex Vivo Culture for the Study of Myofibroblasts and Extracellular Matrix Interactions
Published on: April 18, 2015
'Firebreak' grafts in Dupuytren's contracture
Abstract:
The empirical observation that Dupuytren's Contracture does not recur beneath a skin graft is applied as a means of controlling recurrent Dupuytren's Disease. In those patients with a strong inherited diathesis to the production of Dupuytren's Contracture, recurrence may occur or even by anticipated, and the placement of a skin graft strategically at a flexion crease is shown to act as a 'firebreak' between areas of potential flare-up of recurrent Dupuytren's Disease.
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