[Iopromide, a new contrast medium for angiography. Clinical study and comparison with other low-osmolar contrast...

In a multi-centre randomized double-blind study the ionic dimer ioxaglate was compared with the nonionic monomer iopromide. In a second randomized double-blind study iopamidol was included in the trial. It was shown that with low-osmolar substances sensitivity to pain and warmth occurred to only a slight extent, whether the contrast medium was ionic or non-ionic. An advantage of the non-ionic preparation was the definitely lower incidence of skin-rash, dizziness, nausea and vomiting.