Related Experiment Videos
Cardiac operations in patients with functioning renal allografts
The Journal of Thoracic and Cardiovascular Surgery
|October 1, 1984
Summary
Cardiac surgery is safe for kidney transplant patients with functioning allografts. This study shows acceptable survival and preserved renal function after these complex procedures.
Area of Science:
- Cardiology
- Nephrology
- Transplant Surgery
Background:
- Over 2,000 kidney transplants performed at University of Minnesota Hospitals.
- 14 patients developed cardiac conditions requiring surgery post-transplant (9-144 months interval).
- Mean patient age 42 years, 36% diabetic, all with functioning renal allografts.
Purpose of the Study:
- To evaluate the safety and outcomes of cardiac operations in patients with functioning renal allografts.
- To assess patient survival and preservation of renal function post-cardiac surgery.
Main Methods:
- Retrospective review of 14 kidney transplant recipients who underwent cardiac surgery.
- Procedures included aorta-coronary saphenous vein bypass grafting, valve replacement, and aneurysmectomy.
- Analysis of perioperative and long-term outcomes, including survival and renal function.
Main Results:
- 10 patients had coronary artery bypass grafting, 1 had bypass + aneurysmectomy, 2 had endocarditis treatment, 1 had aortic valve replacement + coronary bypass.
- 14% perioperative mortality (2 patients).
- 7% late mortality (1 patient at 45 months).
- 11 surviving patients remain well (8-93 months post-op), with preserved renal function (mean creatinine 1.6 mg/100 ml).
Conclusions:
- Cardiac operations can be performed safely in patients with functioning renal allografts.
- Patient survival is acceptable following cardiac surgery.
- Renal function is uniformly preserved in surviving patients.