[Reproduction and assembly of oncoviruses]

Modern investigations of structural and functional organization of oncoviruses are analyzed. The data available in the literature on oncovirus interaction with host cell membrane (adsorption, penetration by endocytosis and fusion, uncoating) as well as the cell and viral receptors are elucidated. The results of the studies on retroviral organization of genome, its integration with cellular genome, transcription and translation are given. The functions of long terminal repeats are described. The characteristic of the end step of life cycle of retroviruses (assembly, budding and maturation) is presented.