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Related Experiment Videos

[Prospects for using platinum coordination compounds possessing antitumor activity].

E P Sidorik, A P Burlaka, O A Sirdorik

    Eksperimental'Naia Onkologiia
    |January 1, 1984
    PubMed
    Summary

    Platinum complexes, including cis-diamminedichloroplatinum (cisplatin), are effective chemotherapy agents for various cancers. This review analyzes their clinical applications and optimal treatment regimens for improved patient outcomes.

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    Redox state of adipose tissue for patients with gastric cancer and its connection with the body mass index and distance from the tumor.

    Obesity research & clinical practice·2019

    Area of Science:

    • Oncology
    • Medicinal Chemistry

    Context:

    • Platinum-based chemotherapy is a cornerstone in cancer treatment.
    • Cis-diamminedichloroplatinum (cisplatin) is a widely studied platinum complex.

    Purpose:

    • To provide a comprehensive analysis of experimental and clinical studies on platinum complexes.
    • To highlight the efficacy of platinum complexes in treating specific cancers and drug-resistant tumors.

    Summary:

    • Platinum complexes, particularly cisplatin, demonstrate significant antiblastic activity.
    • Effective in treating ovarian, testicular, lung, head and neck, and bladder cancers.
    • Shows efficacy against tumors resistant to alkylating agents and other chemotherapeutics.

    Impact:

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  • Systematizes clinical data to guide the selection of optimal platinum complex treatment regimens.
  • Aims to improve therapeutic strategies for various solid tumors.
  • Facilitates evidence-based decision-making in clinical oncology.