Related Experiment Videos
Dynamics of ribosomal RNA structure
V A Erdmann1, M Digweed, T Pieler
1Institut für Biochemie, Freie Universität Berlin, Federal Republic of Germany.
Journal of Biomolecular Structure & Dynamics
|December 1, 1983
Abstract:
The structural dynamics of ribosomal 5S RNAs have been investigated by probing single strandedness through enzymatic cleavage and chemical modification. This comparative study includes 5S rRNAs from E. coli, B. stearothermophilus, T. thermophilus, H. cutirubrum, spinach chloroplast, spinach cytomplasm, and Artemia salina. The structural studies support a unique tertiary interaction in eubacterial 5S rRNAs, involving nucleotides around positions 43 and 75. In addition long range structural effects are demonstrated in E. coli 5S rRNA due to the conversion of C to U at position 92.