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Related Experiment Videos

Cold pressor test and variant angina.

T Kawano, M Okabe, K Arakawa

    Angiology
    |July 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    The cold pressor test can induce coronary artery spasm and total occlusion in patients with variant angina. Cold exposure poses an additional risk for individuals with this condition.

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    Area of Science:

    • Cardiology
    • Clinical Medicine
    • Diagnostic Testing

    Background:

    • Variant angina is characterized by coronary artery spasm.
    • The cold pressor test is a known stimulus for physiological responses.

    Observation:

    • A 51-year-old man with variant angina underwent a cold pressor test.
    • Coronary arteriography revealed normal left coronary artery and minor right coronary artery irregularities pre-test.
    • During cold stimulation, the patient experienced angina with ST-segment elevation.

    Findings:

    • Simultaneous arteriography showed complete proximal right coronary artery occlusion due to spasm during the anginal attack.
    • Nitroglycerin administration resolved the angina and coronary artery spasm.
    • The cold pressor test successfully triggered coronary artery spasm and total occlusion.

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    Implications:

    • The cold pressor test can precipitate acute coronary events in variant angina patients.
    • Cold exposure represents a significant risk factor for individuals with variant angina.
    • This study highlights the utility of provocative testing in diagnosing and understanding variant angina triggers.