Polycystic ovary disease in two patients with Briquet's disorder

Luteinizing hormone, testosterone, and follicle-stimulating hormone were evaluated by radioimmunoassay in two patients with Briquet's disorder, secondary depression, and menstrual irregularity. In both patients a hormonal pattern consistent with polycystic ovary disease was documented. The ovaries of both patients showed the classic pathologic findings of this disease. These results suggest that the hormonal and ovarian pathologic abnormalities of polycystic ovary disease may be common in patients with menstrual irregularity and Briquet's disorder.