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Updated: Aug 17, 2026

Expired CO2 Measurement in Intubated or Spontaneously Breathing Patients from the Emergency Department
Published on: January 29, 2011
Effects of alaproclate and morphine on the ventilatory response to carbon dioxide in normal man
Abstract:
The ventilatory response to carbon dioxide was determined in six healthy volunteers given alaproclate alone and combined with morphine. A rebreathing technique was used and the slope of the ventilatory response to carbon dioxide was plotted. A comparison of these responses after alaproclate or a placebo showed no significant difference. Following the administration of morphine i.v., respiration was depressed, but there was no enhancement of the depression of the ventilatory response to carbon dioxide in subjects pretreated with alaproclate.
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