Orientation shift between upper and lower layers in monkey visual cortex
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Updated: Oct 23, 2026

Where You Cut Matters: A Dissection and Analysis Guide for the Spatial Orientation of the Mouse Retina from Ocular Landmarks
Published on: August 4, 2018
Abstract:
Microelectrode penetrations nearly normal to the layers of foveal striate cortex in awake, behaving monkeys reveal a shift in orientation preference between cells in the upper and lower layers. Mean shift size for 57 penetrations is 54.8 degrees, with 70% of the penetrations showing shifts of 45-90 degrees. Marking lesions localize the shift to the border between layers 4C and 5. The data are suggestive of inhibition between the upper and lower layers within an "orientation column".
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