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Abolishment of the Ranvier node excitability under quasi-total deuteration and rhythmic stimulation
Physiologie (Bucarest)
|April 1, 1983
Abstract:
The isolated nerve fibre, when quasi-totally deuterated, loses its excitability after about 15' of rhythmic stimulation at frequencies of 150-200 Hz. It is only on internal rehydration that excitability is recovered at high frequencies of stimulation. An excitation-energy coupling is suggested to exist, which appears to be more obvious at high frequencies of stimulation and strongly affected by the proton-deuteron exchange in the intracellular medium.
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