Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exercise hyperpnea in the duck without intrapulmonary chemoreceptor involvement.

J P Kiley, M R Fedde

    Respiration Physiology
    |September 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Structural and oxidative enzyme characteristics of the diaphragm.

    Equine veterinary journal. Supplement·2002
    Same author

    Ventilatory sensitivity to changes in inspired and arterial carbon dioxide partial pressures in the chicken.

    Poultry science·2002
    Same author

    Methods for obtaining and analyzing unattended polysomnography data for a multicenter study. Sleep Heart Health Research Group.

    Sleep·2001
    Same author

    Cardiorespiratory impact of the nitric oxide synthase inhibitor L-NAME in the exercising horse.

    Respiration physiology·2000
    Same author

    Analysis of the right ventricular function in the exercising horse: use of the Fourier Transform.

    Equine veterinary journal·2000
    Same author

    Cardio-pulmonary function in preascitic (hypoxemic) or normal broilers inhaling ambient air or 100% oxygen.

    Poultry science·2000

    Intrapulmonary chemoreceptors (IPC) do not drive increased breathing during exercise in ducks. This study demonstrates that ventilation increases due to other neural inputs, possibly from muscles, not IPC.

    Area of Science:

    • Physiology
    • Respiratory Control
    • Exercise Physiology

    Background:

    • Intrapulmonary chemoreceptors (IPC) play a role in regulating breathing.
    • Their involvement in exercise-induced hyperpnea is not fully understood.
    • Maintaining a constant microenvironment for IPC is crucial for studying their role.

    Purpose of the Study:

    • To investigate the role of intrapulmonary chemoreceptors (IPC) in controlling breathing during exercise.
    • To determine if IPC are essential for the increase in ventilation observed during physical activity.
    • To identify alternative neural pathways responsible for exercise-induced hyperpnea.

    Main Methods:

    • Unanesthetized Pekin ducks were used with a surgical procedure to isolate one lung.
    • The left pulmonary artery was ligated, diverting blood flow to the denervated right lung.

    Related Experiment Videos

  • The isolated left lung was unidirectionally ventilated with a constant gas mixture, maintaining a stable PCO2 microenvironment for IPC.

    • Main Results:

    • Ventilatory effort significantly increased by 145% during running exercise.
    • This increase was due to higher respiratory frequency and tidal volume.
    • The experimental setup ensured that IPC were not exposed to altered stimuli during exercise.

    Conclusions:

    • Increased ventilation during exercise in ducks can occur independently of intrapulmonary chemoreceptor stimulation.
    • The findings suggest that other neural inputs, potentially originating from muscles, mediate the hyperpnea of exercise.
    • This research highlights the complexity of respiratory control during physical exertion.