Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Arthritis associated with lithium toxicity: case report.

D W Black, R Waziri

    The Journal of Clinical Psychiatry
    |March 1, 1984
    PubMed
    Summary

    Lithium toxicity can cause temporary joint pain (polyarthritis) in patients. Discontinuing lithium treatment resolved the arthritis, suggesting a potential link between lithium, autoimmunity, and joint inflammation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Genome-wide association study of obsessive-compulsive disorder.

    Molecular psychiatry·2012
    Same author

    A morphological and functional study on a cluster of identifiable neurosecretory cells in the abdominal ganglion of aplysia californica.

    The Journal of cell biology·2009
    Same author

    Predictors of response to Systems Training for Emotional Predictability and Problem Solving (STEPPS) for borderline personality disorder: an exploratory study.

    Acta psychiatrica Scandinavica·2009
    Same author

    Can Too Much Sex be a Bad Thing?

    CNS spectrums·2008
    Same author

    The epidemiology and phenomenology of compulsive sexual behavior.

    CNS spectrums·2008
    Same author

    Sexual disorders not otherwise specified: compulsive, addictive, or impulsive?

    CNS spectrums·2008

    Area of Science:

    • Rheumatology
    • Clinical Toxicology
    • Psychopharmacology

    Background:

    • Lithium is a mood-stabilizing medication widely used in treating bipolar disorder.
    • While effective, lithium can have various side effects, including potential effects on the immune system and joints.
    • The precise mechanisms underlying lithium's impact on rheumatological conditions are not fully understood.

    Observation:

    • A case study involving a 33-year-old male patient experiencing transient polyarthritis.
    • The patient was undergoing lithium therapy, and the onset of joint pain coincided with elevated lithium levels.
    • Arthritic symptoms included swelling and pain in multiple joints, characteristic of polyarthritis.

    Findings:

    • The patient's polyarthritis resolved completely after the cessation of lithium treatment.
    • This resolution strongly suggests a direct causal relationship between lithium exposure and the development of arthritic symptoms.
    • Blood tests and clinical evaluation did not reveal other common causes of polyarthritis.

    Implications:

    • This case highlights a potential adverse effect of lithium therapy, specifically the induction of transient polyarthritis.
    • The findings postulate a possible role for autoimmune mechanisms in lithium-induced arthritis.
    • Further research is warranted to elucidate the link between lithium, autoimmunity, and joint inflammation, potentially informing safer prescribing practices.

    Related Experiment Videos