[Content of serotonin, catecholamines and monoamine oxidase activity of the lung in disease]

Metabolism of catecholamines and serotonin was studied in experiments with ischemia of respiratory tissue and hypoxic hypoxia, in cases of acute and chronic inflammatory bronchopulmonary processes as well as in lung homogenates obtained from patients with bronchiectases. Long-term effects of ischemia, hypoxia and chronic inflammatory bronchopulmonary process caused inhibition of oxidative deamination of monoamines, as a result of which the barrier function of lung might be impaired.