Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postmarketing surveillance: practical experience with ketotifen.

W P Maclay, D Crowder, S Spiro

    British Medical Journal (Clinical Research Ed.)
    |March 24, 1984
    PubMed
    Summary

    Postmarketing surveillance of ketotifen (Zaditen) for asthma prophylaxis found it effective in 70% of patients. This study confirmed known efficacy and safety, similar to clinical trials, with no unexpected side effects.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Fifteen-year trends and predictors of preparation for pregnancy in women with pre-conception Type 1 and Type 2 diabetes: a population-based cohort study.

    Diabetic medicine : a journal of the British Diabetic Association·2014
    Same author

    Universal screening to identify gestational diabetes: a multi-centre study in the North of England.

    Diabetes research and clinical practice·2013
    Same author

    Funnel plots for comparing institutional performance of antenatal care in pregnant women with diabetes.

    The Ceylon medical journal·2012
    Same author

    Benefit:risk consideration in long-term therapy with dexfenfluramine.

    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity·1992
    Same author

    Developing a new uniform policy for student nurses.

    British journal of nursing (Mark Allen Publishing)·1992
    Same author

    Effects of selective histamine receptor antagonists on skin responses to intradermal bradykinin in healthy volunteers.

    The Journal of pharmacy and pharmacology·1992

    Area of Science:

    • Pharmacology
    • Clinical Pharmacy
    • Respiratory Medicine

    Background:

    • Ketotifen (Zaditen) is an oral medication used for preventing bronchial asthma attacks.
    • Postmarketing surveillance is crucial for evaluating real-world drug performance and safety.

    Purpose of the Study:

    • To assess the adverse events and efficacy of ketotifen in a large patient cohort.
    • To evaluate the collaborative process between industry, regulatory bodies, and healthcare providers.

    Main Methods:

    • A one-year postmarketing surveillance study involving 8291 patients with asthma.
    • Regular data collection every three months to record adverse events and subjective efficacy.

    Main Results:

    • Subjective assessment indicated that 70% of patients found ketotifen efficacious.

    Related Experiment Videos

  • Adverse events were consistent with those reported in prior clinical trials, with no unexpected or unacceptable findings.
  • The study demonstrated successful collaboration among pharmaceutical industry, regulatory authorities, and prescribing physicians.

    • Conclusions:

    • Ketotifen demonstrates significant efficacy and a favorable safety profile in a broad asthma patient population.
    • The value of large-scale postmarketing surveys in confirming known drug characteristics requires further evaluation.
    • Real-world data collection supports ongoing efforts in medication safety and prescribing practices.