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Related Experiment Videos

[Canthaxanthine retinopathy: 1. Clinical study in 51 consumers].

G Boudreault, P Cortin, L A Corriveau

    Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
    |December 1, 1983
    PubMed
    Summary

    Canthaxanthin, a popular skin-tanning agent, was evaluated in 51 individuals. Ocular fundus deposits were observed in six subjects, but no vision impairment resulted from this carotenoid.

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    Area of Science:

    • Ophthalmology
    • Dermatology
    • Toxicology

    Context:

    • Canthaxanthin, a carotenoid, has been used as a skin-tanning agent in Canada since 1979.
    • Concerns exist regarding potential ocular side effects of long-term canthaxanthin ingestion.

    Purpose:

    • To evaluate the ophthalmological effects of ingested canthaxanthin in individuals using it as a tanning agent.

    Summary:

    • Fifty-one individuals ingested between 3.6 and 66 g of canthaxanthin over 24 months.
    • Ophthalmological examinations revealed ocular fundus deposits in six subjects.
    • No functional visual impairment was detected in any of the evaluated individuals.

    Impact:

    • Suggests that while canthaxanthin can cause ocular deposits, it may not lead to functional vision loss.

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  • Highlights the need for continued monitoring of carotenoid supplements for potential adverse effects.
  • Informs dermatologists and ophthalmologists about potential ocular findings associated with canthaxanthin use.