Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gonadotropin secretion in hyperthyroidism and hypothyroidism.

G Valenti, G P Ceda, L Denti

    La Ricerca in Clinica E in Laboratorio
    |January 1, 1984
    PubMed
    Summary

    Thyroid disease, including hyperthyroidism, significantly impacts gonadotropin levels, particularly luteinizing hormone (LH). Treatment restoring euthyroid states normalizes these hormone patterns in both sexes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Search for CP Violation in D_{s}^{+}→K_{S}^{0}π^{+}, D^{+}→K_{S}^{0}K^{+}, and D^{+}→ϕπ^{+} Decays.

    Physical review letters·2019
    Same author

    Search for Lepton-Universality Violation in B^{+}→K^{+}ℓ^{+}ℓ^{-} Decays.

    Physical review letters·2019
    Same author

    Model-Independent Observation of Exotic Contributions to B^{0}→J/ψK^{+}π^{-} Decays.

    Physical review letters·2019
    Same author

    First Measurement of Charm Production in its Fixed-Target Configuration at the LHC.

    Physical review letters·2019
    Same author

    Measurement of the Charm-Mixing Parameter y_{CP}.

    Physical review letters·2019
    Same author

    Observation of Two Resonances in the Λ_{b}^{0}π^{±} Systems and Precise Measurement of Σ_{b}^{±} and Σ_{b}^{*±} Properties.

    Physical review letters·2019

    Area of Science:

    • Endocrinology
    • Reproductive Medicine
    • Thyroidology

    Background:

    • Thyroid dysfunction, including Graves' disease and primary hypothyroidism, affects numerous bodily systems.
    • Hormonal imbalances in thyroid disorders can influence reproductive health and pituitary function.

    Purpose of the Study:

    • To investigate the patterns of gonadotropins (hormones regulating reproductive functions) in patients with Graves' disease and primary hypothyroidism.
    • To assess the impact of thyroid status on gonadotropin levels in both males and females.
    • To explore the recovery of gonadotropin function after therapeutic normalization of thyroid hormone levels.

    Main Methods:

    • Evaluation of basal and stimulated gonadotropin levels (including LH and FSH) in 70 patients.
    • Comparison of hormone patterns between hyperthyroid, hypothyroid, and euthyroid states.
    • Analysis of hormonal changes in relation to sex and age.

    Main Results:

    • Significant alterations in gonadotropin levels, especially elevated LH, were observed in hyperthyroid patients.
    • Qualitative and quantitative recovery of gonadotropin patterns occurred upon achieving euthyroid status after treatment.
    • Interactions between thyroid status and gonadotropin behavior were noted across both sexes and different age groups.

    Conclusions:

    • Hyperthyroidism directly affects the hypothalamo-pituitary axis, leading to altered gonadotropin secretion.
    • The observed changes in gonadotropins are likely due to direct interference with the hypothalamo-pituitary system, not solely through estrogen metabolism modulation.
    • Restoration of euthyroid state is crucial for normalizing reproductive hormone function in thyroid disease patients.

    Related Experiment Videos