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[Retinopathy due to canthazanthine: 2. Predisposing factors].

P Cortin, G Boudreault, A P Rousseau

    Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
    |August 1, 1984
    PubMed
    Summary

    Certain factors increase susceptibility to retinopathy from canthaxanthine, a skin-tanning agent. These include focal epitheliopathy, ocular hypertension, and concurrent beta-carotene use, alongside age.

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    Canthaxanthin retinopathy. Anatomic and functional reversibility.

    Archives of ophthalmology (Chicago, Ill. : 1960)·1989

    Area of Science:

    • Ophthalmology
    • Toxicology
    • Dermatology

    Context:

    • Canthaxanthine, a carotenoid, is used as a synthetic skin-tanning agent.
    • Retinopathy is a potential adverse effect associated with its use.
    • Understanding risk factors is crucial for patient safety.

    Purpose:

    • To identify clinical factors associated with canthaxanthine-induced retinopathy.
    • To investigate the role of focal epitheliopathy, ocular hypertension, and beta-carotene in susceptibility.
    • To build upon established risk factors like age.

    Summary:

    • A retrospective study analyzed 14 cases of retinopathy linked to canthaxanthine.
    • Focal epitheliopathy, ocular hypertension, and concurrent beta-carotene use were associated with increased retinal deposits.

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  • Age was confirmed as a predisposing factor.

    • Impact:

    • Highlights potential risks of canthaxanthine as a tanning agent.
    • Informs clinicians about patient susceptibility to retinopathy.
    • Suggests further research into carotenoid ocular toxicity.