Biochemical activity of intestinal microflora in adult coeliac disease

In order to answer up to now open questions regarding the role of the microflora in the pathophysiology of adult coeliac disease the excretion of bacterial metabolites in urine has been followed. Unusual high outputs of p-cresol and/or phenol were found in almost all patient, whereas an increased excretion of indican could be observed in a few persons, only. The response to short-term antibacterial therapy was variable.