CT of acquired immunodeficiency syndrome

Thirty patients with acquired immunodeficiency syndrome were examined by computed tomography. In addition to systemic disease, these patients had a variety of neurologic symptoms and signs. Cerebral toxoplasmosis (six cases) was generally manifested by ring-enhancing lesions with surrounding decreased attenuation. Lymphoma (one case) exhibited a solid enhancing nodule, and progressive multifocal leukoencephalopathy (two cases) showed periventricular decreased attenuation. Atrophy (15 cases) was very common and invariably indicated a poor prognosis; the autopsy examinations of the latter cases showed degeneration of gray and white matter with features similar to cytomegalic inclusion encephalitis and subacute sclerosing encephalopathy of measles.