Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Observations on computerized quantitative bone scintigraphy in renal osteodystrophy.

P de Graaf, E K Pauwels, P H Vos

    European Journal of Nuclear Medicine
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Correlation between head and neck radiologists reporting on extranodal extension detected on radiological imaging: A head and neck cancer international group multinational study.

    Oral oncology·2026
    Same author

    Visual outcome including visual field defects after treatment of paediatric optic pathway glioma: A nationwide cohort study.

    Acta ophthalmologica·2025
    Same author

    Use of Diffusion-Weighted Imaging and <sup>18</sup>F-Fluorodeoxyglucose Positron Emission Tomography Combined With Computed Tomography in the Response Assessment for (Chemo)radiotherapy in Head and Neck Squamous Cell Carcinoma.

    Clinical oncology (Royal College of Radiologists (Great Britain))·2018
    Same author

    The multilayered structure of the human corpus spongiosum.

    Histology and histopathology·2018
    Same author

    Recurrent Optic Perineuritis after Intranasal Cocaine Abuse.

    Neuro-ophthalmology (Aeolus Press)·2016
    Same author

    3D Orbital Reconstruction in a Patient with Microphthalmos and a Large Orbital Cyst-A Case Report.

    Ophthalmic genetics·2016

    Computerized skeletal analysis using 99mTc-HEDP radiotracer uptake effectively detects renal osteodystrophy in dialysis patients. This method correlates with bone turnover, suggesting hyperparathyroidism as a primary cause.

    Area of Science:

    • Nuclear Medicine
    • Nephrology
    • Pathology

    Background:

    • Renal osteodystrophy is a common complication in chronic dialysis patients.
    • Elevated soft-tissue radiotracer activity can interfere with scintigraphic assessment.

    Purpose of the Study:

    • To evaluate the efficacy of computerized quantitative skeletal analysis using 99mTc-HEDP in detecting renal osteodystrophy.
    • To correlate radiotracer uptake with histologic bone findings and hyperparathyroidism.

    Main Methods:

    • Quantitative scintigraphy of skeletal radiotracer (99mTc-HEDP) uptake in 30 dialysis patients.
    • Hemodialysis was used to reduce soft-tissue activity before imaging.
    • Computerized analysis of skeletal uptake was compared with normal subjects and bone morphometric studies.

    Related Experiment Videos

    Main Results:

    • All patients showed elevated skeletal radiotracer uptake.
    • Computerized analysis distinguished most patients from normal controls, despite residual soft-tissue activity.
    • Skeletal uptake correlated significantly with bone biopsy findings of increased bone turnover.

    Conclusions:

    • Computerized quantitative skeletal analysis is a promising scintigraphic method for diagnosing renal osteodystrophy.
    • Increased radiotracer uptake is primarily linked to hyperparathyroidism in renal osteodystrophy.