[Subcorneal pustulosis and monoclonal gammapathies]

Subcorneal pustular dermatosis (Sneddon-Wilkinson) is a rare dermatosis. In some cases, it is associated with a monoclonal gammopathy, most often Ig A. This association is considered as a salient feature of SPD, and is not present in other pustuloses, like pustular psoriasis, which may be related to SPD. The physiopathology of the neutrophilic dermatoses and the role of Ig A are briefly discussed.