Effects of prostaglandins E-1, E-2, F-1a and F-2a on human sperm motility

Effects of the addition of 100 micrograms each of prostaglandins E1, E2, F1a and F2a were seen on the motility, fructose utilization and total ATPase activity of human spermatozoa. PGE2 enhanced sperm motility and fructose utilization and decreased the whole sperm ATPase activity. While PGE1 had no effect on any of the parameters studied, PGF1a and PGF2a decreased sperm motility to some extent. Fructose utilization was reduced after PGF1a addition only. No change in the activity of ATPase was observed after treatment with F series of prostaglandins.