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Asthma and atopy in workers with an epoxy adhesive
British Journal of Diseases of the Chest
|April 1, 1980
Summary
Workers exposed to epoxy adhesives may experience respiratory issues like wheezing. A simple questionnaire can help screen for sensitization to these chemicals.
Area of Science:
- Occupational Health
- Toxicology
- Pulmonary Medicine
Background:
- Epoxy adhesives, particularly those cured with pyromellitic dianhydride, are used in various industrial settings.
- Worker exposure during mixing and application necessitates understanding potential respiratory health impacts.
Observation:
- Seven workers using epoxy adhesive were monitored for respiratory symptoms and lung function (FEV1).
- Questionnaires assessed pre-existing conditions, atopy, smoking history, and adhesive-related symptoms.
- Skin tests for common allergens were also conducted.
Findings:
- Two workers reporting wheezing experienced significant declines in forced expiratory volume in 1 second (FEV1) of 15% and 18%.
- Asymptomatic workers showed minimal FEV1 changes (<4%) or improvement.
- No clear correlation was found between smoking, atopy, or skin reactions and FEV1 decline.
Implications:
- Identifying individuals at risk for epoxy adhesive-induced wheezing is challenging.
- Careful handling of epoxy adhesives is crucial to prevent sensitization.
- A simple questionnaire may serve as a practical screening tool for detecting sensitization.