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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Related Experiment Video

Updated: Dec 27, 2025

A Silicosis Mouse Model Established by Repeated Inhalation of Crystalline Silica Dust
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Clinical and radiological study in sepiolite workers.

Y I Baris, A A Sahin, M L Erkan

    Archives of Environmental Health
    |November 1, 1980
    PubMed
    Summary

    Sepiolite dust exposure did not cause mineral fiber-related pleural diseases. Pulmonary fibrosis in workers was linked to smoking and asbestos exposure, not sepiolite inhalation.

    Area of Science:

    • Occupational Health
    • Pulmonology
    • Environmental Medicine

    Background:

    • Sepiolite mining and processing have a long history in Eskisehir, Turkey.
    • Potential health risks associated with mineral dust exposure are a significant concern.

    Purpose of the Study:

    • To investigate radiological findings in populations exposed to sepiolite dust.
    • To assess the relationship between sepiolite exposure and respiratory diseases, specifically pleural diseases and pulmonary fibrosis.

    Main Methods:

    • Mass radiological survey using 70 mm films in four villages with sepiolite mining.
    • Clinical and radiological study of 63 sepiolite trimming workers.

    Main Results:

    • No cases of mineral fiber-related pleural diseases were detected in individuals exposed to sepiolite dust.

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  • Pulmonary fibrosis was observed in 10 out of 63 workers, but this was not directly linked to sepiolite inhalation.
  • All patients with pulmonary fibrosis were smokers and originated from areas with tremolite (asbestos) and zeolite presence.

    • Conclusions:

    • Occupational exposure to sepiolite dust in the studied population did not lead to mineral fiber-related pleural diseases.
    • Pulmonary fibrosis in sepiolite workers appears to be associated with smoking and co-exposure to other environmental dusts like asbestos, rather than sepiolite itself.