Related Experiment Video
Updated: Aug 14, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Early post-operative changes in left ventricular dimensions and mass following valve replacement in adults with
Abstract:
Twelve adults with isolated valvular aortic stenosis (AS) were evaluated for early changes of left ventricular (LV) dimensions and mass (LVM/M2) following valve replacement (AVR). M-mode echocardiography was performed pre- and 3 to 5 weeks post-AVR. LV internal diameter (LVID) decreased from 51 +/- 2.0 to 46 +/- 2.7 mm post-AVR (p less than .02). Reduction of posterior wall thickness (PWT) from 12 +/- 0.7 to 10 +/- 0.6 mm (p less than .01), interventricular septal thickness (IVST) from 13 +/- 0.9 to 11 +/- 1.2 mm (p less than .005), and mean myocardial thickness (MMT) from 12.4 +/- 0.7 to 10.5 +/- 0.7 (p less than .001), occurred post-AVR. Wall thickness/internal radius ratio was unchanged post-AVR. Calculated LVM/M2 decreased from 170 +/- 15 to 110 +/- 13 grams post-AVR (p less than .001). Normalized posterior wall velocity (PWVn) increased post-AVR from 0.66 +/- .05 to 1.08 +/- .10 sec-1 (p less than .001). For all twenty four studies, LVM/M2 and PWVn were correlated (r = -0.725, p less than .001). In summary, LV dimensions and LVM/M2 decreased significantly 3 to 5 weeks post-AVR in adults with AS. There was significant correlation of LVM/M2 and PWVn for pre-AVR and post AVR studies.
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